Coala: An R framework for coalescent simulation

Paul R. Staab and Dirk Metzler.
Bioinformatics (2016).

Co-estimation of Demography and Positive Selection

Paul R. Staab.
PhD Thesis.

scrm: efficiently simulating long sequences using the approximated coalescent with recombination

Paul R. Staab, Sha Zhu, Dirk Metzler, and Gerton Lunter.
Bioinformatics 31 (10), 1680-1682.

Why to account for finite sites in population genetic studies and how to do this with Jaatha 2.0

Lisha A. Mathew, Paul R. Staab, Laure E. Rose, and Dirk Metzler.
Ecology and Evolution (2013).

Muller’s ratchet with compensatory mutations

Peter Pfaffelhuber, Paul R Staab and Anton Wakolbinger.
Ann. Appl. Probab. Volume 22, Number 5 (2012), 2108-2132.

Muller’s ratchet with compensatory mutations

Paul R. Staab.
Diploma thesis, 2011.

SynBioWave – a real-time communication platform for molecular and synthetic biology

Paul R Staab, Jorg Walossek, David Nellessen, Raik Grunberg, Katja M. Arndt and Kristian M. Müller.
Bioinformatics (2010).



A simulation based composite-likelihood method to fit an evolutionary model to genetic data.
[Link] [CRAN] [Source]


An efficient coalescent simulator for genome-scale sequences.
[Link] [Source]


Simulates a population of haploids undergoing Muller's Ratchet. Capable of compensatory mutations.
[Source] [Runnable jar file]


A collaborative synthetic biological software suite, based on discontinued Google Wave.


I'm a Data Scientist in Munich, Germany.

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